細胞名稱

人前列腺癌細胞C4-2

貨物編碼

BFN60807475

產(chǎn)品規(guī)格

T25培養(yǎng)瓶x1

1.5ml凍存管x2

細胞數(shù)量

1x10^6

1x10^6

保存溫度

37℃

-198℃

運輸方式

常溫保溫運輸

干冰運輸

安全等級

1

用途限制

僅供科研        1類

培養(yǎng)體系

DMEM高糖培養(yǎng)基+10%FBS+1%三抗 

培養(yǎng)溫度

37℃

二氧化碳濃度

5%

簡介

人前列腺癌細胞C4-2取自50歲男性供體

注釋

Characteristics: Exhibits androgen independent growth associated with skeletal metastasis, produces metastases when injected either subcutaneously or orthotopically in intact or castrated mice.

Doubling time: 28.96 hours 

基因突變

Homozygous for AR p.Thr878Ala (c.2632A>G) (from parent cell line).

Heterozygous for MEN1 p.Tyr313Ter (c.939T>A) (from parent cell line).

Heterozygous for PIK3R1 p.Arg639Ter (c.1915C>T) (from parent cell line)

HLA信息

/

STR信息

/

參考文獻

PubMed=8169003; DOI=10.1002/ijc.2910570319

Wu H.-C., Hsieh J.-T., Gleave M.E., Brown N.M., Pathak S., Chung L.W.K.

Derivation of androgen-independent human LNCaP prostatic cancer cell sublines: role of bone stromal cells.

Int. J. Cancer 57:406-412(1994)

PubMed=15162376; DOI=10.1002/pros.20031

Liu A.Y., Brubaker K.D., Goo Y.A., Quinn J.E., Kral S., Sorensen C.M., Vessella R.L., Belldegrun A.S., Hood L.E.

Lineage relationship between LNCaP and LNCaP-derived prostate cancer cell lines.

Prostate 60:98-108(2004)